cyclosporin A

cyclosporin A
(= ciclosporine)
Cyclic undecapeptide isolated from Tolypocladium inflatum, that has potent immunosuppressant activity on both humoral and cellular systems. The use of cyclosporin has made transplant surgery much easier, although the long-term consequences of suppressing immune function are not yet clear. Used widely as an an anti-rejection drug in transplant surgery. See also cyclophilin.

Dictionary of molecular biology. 2004.

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Look at other dictionaries:

  • cyclosporin — cyclosporin, cyclosporine cyclosporine . a chemical substance produced by some soil fungi, which suppresses the cellular immune response by inhibiting T cell activation, and has been used in medicine to reduce foreign tissue rejection, especially …   The Collaborative International Dictionary of English

  • Cyclosporin A — См. Циклоспорин A (Источник: «Словарь терминов микробиологии») …   Словарь микробиологии

  • cyclosporin A — cyclosporin A. См. циклоспорин А. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • Cyclosporin A — Cyclosporin A,   Ciclosporin das, , internationaler Freiname für ein aus dem Bodenpilz Tolypocladium inflatum gewonnenes zyklisches Polypeptid, das als Immunsuppressivum v. a. zur Verhütung von Transplantatabstoßungen eingesetzt wird; hemmt die… …   Universal-Lexikon

  • Cyclosporin — Strukturformel Allgemeines Freiname Ciclosporin Andere Namen Cy …   Deutsch Wikipedia

  • Cyclosporin A — Strukturformel Allgemeines Freiname Ciclosporin Andere Namen Cy …   Deutsch Wikipedia

  • cyclosporin A — SYN: cyclosporine. * * * cyclosporin A n CYCLOSPORINE * * * cy·clo·spor·in A (si″klo sporґin) cyclosporine …   Medical dictionary

  • cyclosporin — [ˌsʌɪklə(ʊ) spɔ:rɪn] (also cyclosporin A, cyclosporine) noun Medicine an immunosuppressive drug obtained from a fungus, used to prevent the rejection of grafts and transplants. Origin 1970s: from cyclo + sporin (from L. spora spore ) + in1 …   English new terms dictionary

  • cyclosporin A — noun see cyclosporine * * * cyclosporin A /sī klō spörˈin ā/ noun An immunosuppressant drug used following transplant surgery to reduce the risk of tissue rejection ORIGIN: ↑cyclo and Gr spora seed …   Useful english dictionary

  • cyclosporin — noun see cyclosporine …   New Collegiate Dictionary

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